We built AssetOS to de-risk asset strategy.

    Strategic decisions on assets are typically made in silos over months to years. We change that. AssetOS is a reasoning and synthesis software platform optimising your asset decisions as new evidence lands.

    NLRP3

    Build your asset strategy.

    Indication strategy

    Gout, heart failure or Parkinson’s?

    Compare the evidence required to advance an NLRP3 inhibitor in each indication.

    Feasibility & safety

    What exposure does each indication require?

    Distinguish short-course, chronic and CNS exposure requirements for the candidate.

    Development plan

    Which study would change the lead indication?

    Order the studies around the evidence missing from each indication path.

    Clinical & regulatory strategy

    What would establish proof of concept?

    Connect pain, cardiac function and CNS readouts to their respective clinical questions.

    Competition & market

    Where could NLRP3 inhibition offer an advantage?

    Compare the proposed benefit with current care and competing NLRP3 programs.

    IP & FTO screening

    Which claims constrain an NLRP3 inhibitor?

    Potential blocking claims identified for counsel's review.

    Partnering & licensing

    Who could advance the selected indication?

    Potential partners and licensing routes matched to the asset's stage and evidence.

    Go/no-go

    What evidence justifies the next investment?

    The case for advancing, unresolved risks and findings that could change the decision.

    AssetOS

    Evidence monitoring
    Indication strategy8 workstreams

    Indication strategyComparison in progress

    Feasibility & safetyCNS exposure unresolved

    Development plan3 studies in progress

    Clinical & regulatory strategy

    Competition & market

    IP & FTO screening

    Partnering & licensing

    Go/no-goAwaiting readouts

    NLRP3

    Indication strategy

    View evidence

    Gout

    Acute flare

    1. Dose-ranging trial

    Insufficient pain benefit → deprioritise gout.

    Heart failure

    HFrEF

    1. Longer-term efficacy trial

    Biomarker change without functional benefit → reassess the clinical rationale.

    Parkinson’s

    CNS

    1. Clinical proof of concept

    Inadequate brain exposure → close this candidate’s CNS path.

    Controlled gout-flare trial

    In progress
    Population
    Acute gout flare
    Readout
    Target-joint pain
    Study details

    Advancement decision

    Awaiting readout
    Criterion
    Clinically meaningful pain benefit versus comparator.
    Next step
    Dose-ranging trial

    Clinical & regulatory strategy

    Dose-ranging design · Review needed

    One operating system for the full asset lifecycle.

    Connect development planning, regulatory strategy, IP and partnering decisions. Keep the plan current as new evidence changes the asset’s risks and opportunities.

    Evidence monitoring

    Keep the development plan current.

    AssetOS tracks new findings, flags changes in risk and proposes updates to the development plan.

    Sources

    Bring relevant evidence together.

    Draw on scientific literature, trial results, regulatory reviews, patents and company disclosures.

    Reasoning

    See the rationale behind each recommendation.

    See how evidence is weighed, where uncertainty remains and what would change the recommendation.

    Auditability

    Trace each conclusion to its source.

    Follow citations to the original records and see the evidence cutoff used for the assessment.

    AssetOS turns the biology into the plan.

    Under every plan sit our causal disease models. Each conclusion they hand the dossier is a causal graph with a citation on every arrow.

    Let’s talk about your asset.

    We’ll walk through your development plan together and show you where AssetOS can help.